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The CReSS Topography device malfunctioned during some study sessions, and one participant was given the wrong cigarette product during one study session, which resulted in missing data for some subjects, further depleting our sample

Smokers immediately recognize this paradox resolution after switching from other full-flavour brands

Not only is nicotine incredibly addictive, it also causes serious and life-threatening health conditions

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Moreover, e-cigarettes offer the psychological and sociocultural aspects of cigarette smoking that traditional NRT does not, which places e-cigarettes in a unique position as a more desirable combustible cigarette substitute.[24] However, the limited data available thus far suggest that e-cigarettes have either no effect or a net detrimental effect on harm reduction at the population level