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We found that cigarette use was not only disproportionately common among those with a substance use disorder, but that the odds of smoking were five times greater than that of the general population, said Renee Goodwin, the senior author of the study

Except for this, combined with our findings that nicotine exposure significantly reduces the expression of transition proteins and protamines, interestingly, similar variations were detected in the bisphenol A-exposed testes, with inference of histone-to-protamine transition and DNA hypermethylation in spermatozoa 48

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