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Ultimately, it is not possible to assert any definitive conclusions regarding the existence of tolerance in individuals with PMPU unless neurobiological evidence (e.g., alteration/sensitization in specific cerebral circuitries) confirms it

Once we have a clear picture of either TMD or bruxism, we can create a custom nightguard as the first line of treatment

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Performance is weak, so I wear this mostly on a cold day at home where I spray it on often

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