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Acknowledgments We thank all participants, staff, and institutions that have contributed to the NHANES database and the publicly available GWAS database

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Food and Drug Administration (FDA) Vaporizers, E-Cigarettes, and other Electronic Nicotine Delivery Systems (ENDS) Centers for Disease Control and Prevention (CDC) Flavorings-Related Lung Disease Link to CDC Occupational Safety and Health Administration (OSHA) Diacetyl and Food Flavorings National Institute for Occupational Safety and Health (NIOSH) Preventing Lung Disease in Workers Who Use or Make Flavorings Link to NIOSH American Lung Association Popcorn Lung: A Dangerous Risk of Flavored E-Cigarettes