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Simpsons colleague at Opt Health, agrees: Theyre mimicking what your body already does but with more specificity

First-line interventions focus on lifestyle modification, including dietary changes targeting a 600 kcal/day deficit, increased physical activity (aiming for 150 minutes of moderate-intensity exercise weekly), and behavioural support programmes

Buddle L.S., Hanna N.H

10.1007/s10068-020-00779-7 [DOI] [PMC free article] [PubMed] [Google Scholar] Qader, M

REDEFINE Trial Headlines Trial REDEFINE 1 Phase 3 Duration 68 weeks Population (N) 3,417 adults with obesity or overweight + 1 comorbidity, without T2D Key Result 20.4% mean weight change vs 3.0% placebo (treatment-policy)