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NAD+ restores mitochondrial energy production and supports DNA repair at the cellular level

Tsao A, Lin H, Carter B, Lee JJ, Rice D, Vaporciyan AA, Swisher SG , Mehran R, Heymach J, Nilsson M, Youhong F, Nunez M, Diao L, Wang J, Fujimoto J, Wistuba I, Hong W

Moreover, despite that our studies show that GSH depletion and onset of injury occur in parallel, the extrapolation from our in vitro studies imply that GSH depletion caused by TNBS is an extremely rapid process that will take place immediately after TNBS reaches target cells preceding the onset of injury

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(2010-2020, J Physiol Pharmacol, Curr Pharm Des) is de toonaangevende primaire literatuur voor preklinische BPC-157-data