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Introduction Since the mid-twentieth century, the World Health Organization (WHO) has recognized "obesity" as a stand-alone, chronic, non-communicable and preventable disease that remains a major, global public health challenge 1, 2

If you develop severe allergic reactions such as difficulty breathing, facial swelling, or widespread rash after a B12 injection, call 999 or go to A&E immediately, as these may indicate anaphylaxis, though this is extremely rare

Contaminated peptides can cause injection site infections, systemic immune reactions, fever, and other adverse effects

That could change after the committee review in July 2026, but today, it's not approved