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During adolescence, nicotine exposure can disrupt the formation of brain circuits that control attention, learning, and susceptibility to addiction

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Holford co-authored the paper with researchers from Cancer Control Department of Oncology at Georgetown University, and the Department of Epidemiology at the University of Michigan School of Public Health

Nicotine and cotinine stimulate secretion of basic fibroblast growth factor and affect expression of matrix metalloproteinases in cultured human smooth muscle cells