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The topical calcineurin inhibitors tacrolimus and pimecrolimus have been studied, but given their unclear long-term safety profiles, they are not considered first-line treatment (16)

Available online at: (Accessed March 16, 2021) 155 National Institute for Health and Clinical Excellence (NICE)

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Exposure for 24 h with the condensed aerosol identified as Menthol 2 resulted in a significant barrier dysfunction due to a reduction in transepithelial electrical resistance compared to both control and condensed aerosol base, composed of propylene glycol, vegetable glycerin, and nicotine