doi: 10.1021/acsnano.4c02420 107 GoodmanRSJohnsonDBBalkoJM
These studies indicate the important role of microglia in maintaining basal neurogenesis
Alcohol 87:115 Pourfridoni M, Hedayati-Moghadam M, Fathi S, Fathi S, Mirrashidi FS, Askarpour H, Shafieemojaz H, Baghcheghi Y (2024) Beneficial effects of metformin treatment on memory impairment
Various external factors could trigger the release of drugs from these engineered liposomes, for instance, variation in the pH or enzymatic activity (134136)
The most commonly reported side effects include: Nausea : Affecting 12% to 24% of patients with type 2 diabetes and 24% to 31% in weight management trials Diarrhea : 12% to 17% in diabetes trials and 18% to 23% in weight management trials Decreased appetite : 5% to 10% of patients Vomiting : 5% to 10% in diabetes trials and 8% to 12% in weight management trials Constipation : 5% to 7% in diabetes trials and 16% to 17% in weight management trials Dyspepsia : 5% to 9% of patients Abdominal pain : 5% to 9% of patients Alopecia (hair loss) : Reported in weight management trials These symptoms are typically mild to moderate in severity, occur most commonly during dose escalation, and tend to diminish over time as patients develop tolerance
