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Functional enrichment for biological processes and signaling pathways was performed via Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway annotations with the clusterProfiler package (version 4.6.2) in R, which utilizes gene sets from MSigDB

For some context, organizations like the World Health Organization have advised on the regulation of tobacco products, but expiration dates arent mandatory in many places, leaving it to consumers to inspect and decide

It was just such a casual thing, where it was implied that I would be involved

As the Institute of Medicines 2007 A Blueprint for the Nation report summarized well regarding tobacco, we cant take our eye off the ball: the central aim for tobacco policy must continue to be reducing the number of tobacco users through a two-pronged strategy of reducing initiation and facilitating cessation

When the state-level trends are examined by sex in Figure 3 (bottom panel plots), the declining pattern appears similar, with considerable differences by gender in all states/territories