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Footnotes Manuscript source: Invited manuscript Specialty type: Gastroenterology and hepatology Country of origin: Croatia Peer-review report classification Grade A (Excellent): 0 Grade B (Very good): B, B Grade C (Good): 0 Grade D (Fair): 0 Grade E (Poor): 0 Institutional review board statement: The study was reviewed and approved by the Department of Veterinary, Ministry of Agriculture, Republic of Croatia, No: UP/I 322-01/07-01/210 Conflict-of-interest statement: The authors state that they have no conflicts of interest

I., Turanov, A

The primary role of glutathione is to protect cells from oxidative stress

Further clinical studies of TCZ showed improved activity, efficacy, safety, and tolerability results against TNF antagonists methotrexate [94,95,96,97] and ADA [98]

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