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[] Discussion Though a late entrant in Ayurvedic literature, Tambakhu (tobacco) is cited in Yogaratnakara, acknowledging its dual nature mildly Kapha-alleviating yet profoundly Pitta-aggravating in excess, causing Murchha (intoxication), Vamana (vomiting), Virechana (purgation), and Shukra Kshaya (semen depletion)

Brian King, director of the FDAs Center for Tobacco Products said in an agency news release

PLoS ONE 14 , e0221961

Provide them with all the gathered documentation and be prepared to answer any questions they may have about the incident

A library input of 1.8 pM with 1% PhiX (Illumina) spike-in was sequenced using the NextSeq 500 instrument (Illumina) with the NextSeq 500/550 High Output v2.5 Kit (Illumina)