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Cardiovascular Risks: Nicotine causes an immediate increase in heart rate and blood pressure, which can be harmful, especially for individuals with pre-existing heart conditions

Brody AL, Mandelkern MA, London ED, Childress AR, Bota RG, Ho ML et al (2002)

The UK governments tobacco duty rates are reviewed annually, typically increasing in line with inflation plus additional percentage points (5)

The major risk factors may include: The use of cigarettes, cigars, and pipe smoking Long-term or heavy use of tobacco Combined use of smoking and alcohol (greatly increases the risk) Smokers are most likely to develop cancers related to direct chemical damage from tobacco

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