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Gene expression analysis RNA sequencing Liver tissue and skeletal muscle tissue (quadriceps) (~0.5 cm 3 in each case) were extracted immediately after rats were euthanized, placed into Eppendorf tubes with RNA (Invitrogen, catalogue no

As first described by Dixon et al (2) in 2012, ferroptosis is a distinct form of cell death characterized by the accumulation of LPOs (3,4)