the effects of tobacco use on health smoking Harmful Effects of Tobacco on

Nicotine occurs naturally in several plants of the nightshade family

-CBT-diol also demonstrated broad-spectrum antifungal activity, inhibiting the tested fungi including Candida albicans, Fusarium chlamydosporum, Rhizoctonia bataticola, Aspergillus niger, and Alternaria alternata , while -CBT-diol had a weaker inhibition on C

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Additionally, tobacco exposure downregulates p53, a critical tumor suppressor gene, facilitating genomic instability and malignant transformation [34]