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As the completed molecule, GSH serves directly as a substrate and cofactor for multiple glutathione-dependent enzyme systems, making it a valuable research tool for investigating redox chemistry, thiol-disulfide exchange processes, enzyme-cofactor interactions, and glutathione-associated regulatory mechanisms

2,3,9 Antioxidants can reduce the harmful effects of ROS and prevent the processes that cause cellular damage

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Because every nucleophile is potentially a base , and vice versa