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In this report, current smokers refers to people who engaged in past month cigarette use

The FTC report found that tobacco manufacturers sold $1.06 billion of synthetic nicotine lozenges, pouches, and other oral nicotine products in 2022, more than double the $452.8 million sold in 2020

For example, intratracheal instillation of PG in mice for two weeks caused a significant increase in the number of inflammatory cells and lipid-laden macrophages in bronchoalveolar lavage fluid (BALF), pulmonary fibrosis, and a significant decrease in airflow during expiration 35

This is true regardless of the smokers age or the number of years they have smoked

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