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Small interfering RNA (siRNA) targeting GPx4 (Applied Biosystems Life Technologies, s6112), NCOA4 (Applied Biosystems Life Technologies, s15566, s15567), NCOA4 (for in vivo experiment) (Applied Bio systems Life Technologies,s77518), ATG5 (Applied Biosystems Life Technologies, s18159, s18160) and negative control siRNAs (Applied Biosystems Life Technologies, AM4635, AM 4641) were purchased

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