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The findings described here demonstrate that the application of liquid alone can cause large-scale reprogramming of gene expression in differentiated ALI cultures and significant changes to aspects of the cell culture physiology that are of great importance with respect to the ability of the dpHBEC-ALI system to represent key aspects of in vivo respiratory tract physiology

Figure 1 In those having HLA and non-HLA risk scores above the median levels of controls, the AF was 11.4% (95%CI: 6.8 to 15.9) and 12% (95%CI: 7.7 to 16.3), respectively

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"This is the Marlboro story," Landry said