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One of the major innovations is the development of Reduced-Risk Products (RRPs), including heated tobacco devices and electronic nicotine delivery systems (ENDS)

Smoking increases the risk of microvascular complications of diabetes like retinopathy and nephropathy

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Abbreviations CI: Confidence Interval d.f: Degrees of Freedom H: Heterogeneity Statistic (Ratio of deviance to degrees of freedom) LCL: Lower Confidence Limit n: number of estimates included in meta-analysis OR: Odds Ratio REF: 6 character Reference code used to identify a study RR: Relative Risk (used also to indicate any effect estimate including Odds Ratio and Hazard Ratio) UCL: Upper Confidence Limit