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To investigate the underlying mechanisms, we performed subsequent in vivo and in vitro experiments

There was no evidence of teratogenicity when terconazole was administered orally up to 40 mg/kg/day (25x the recommended intravaginal human dose of the suppository formulation) in rats, or 20 mg/kg/day in rabbits, or subcutaneously up to 20 mg/kg/day in rats

The strong nicotine hit can prevent cravings and make the switch easier

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