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The review consolidates experimental evidence that supports the utilization of NAC in bone tissue engineering, underscoring its capacity to improve the osteogenic microenvironment and optimize bone regeneration outcomes

Ethics Informed consent was obtained for the use of human samples in accordance with the Declaration of Helsinki

Arginase 1/2 inhibitor OATD-02: from discovery to First-in-man setup in cancer immunotherapy

Although GPX4 depletion alone failed to affect HSCs function in vivo , Vav1- Gpx4 knockout mice fed with a vitamin E-depleted diet exhibited a reduced number of HSCs and dysregulated hematopoiesis, mainly due to increased ferroptosis [22]

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