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But kicking the butt by 40 means that nearly all the excess risk can be avoided. It is not, however, says the CBC, a magic switch : The researchers cautioned it is not safe to smoke until 40 and then stop because the risk is still substantial. Most of the gains in life expectancy come because the twin risks of heart disease and stroke quickly drop after smoking ends

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Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017alpha and P450 aromatase localized in neurons

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