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Caffeine significantly increases intraocular pressure in most people, especially when consumed in amounts of four or more cups a day.238 If you have glaucoma, this pressure increase can occur at half that amount.239 Experts believe that this results from changes in aqueous humor flow, and studies have shown a remarkable difference in the fluid dynamics of the eye between volunteers given caffeine and those given placebo.240 Perhaps even more serious (because it affects a greater number of people) is the decrease in microcirculation in the eye caused by caffeine

Table 4 Association of serum vitamin B 12 levels with all-cause mortality in different subgroups of patients with MASLD

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4 for a visual representation of these processes