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Passive smoking respiratory risk

Notably, three overlapping metabolites across all comparison groups - L-Asparagine (amino acid biosynthesis), Shikimic acid (amino acid biosynthesis), and 3-Hydroxyanthranilic acid (tryptophan metabolism) - showed consistent downregulation (T0 vs

In addition, chewing tobacco can lead to cancer, oral disease, heart disease, and stroke (11, 12)

Our findings are consistent across multiple tissues and align with other studies that have not observed robust associations between smoking and Horvath clock predictions [102, 103]

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