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Just 30 minutes of exposure to secondhand smoke can cause heart damage similar to that of an everyday smoker

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These chemicals affect ecosystems at every level, from microorganisms through to plants, animals and aquatic life

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Reconciling those two things proved difficult, and de Vis says that Knotts was a good way into his career when he found himself sitting in the office of a Hollywood therapist, screaming "F*** you, God!" in an attempt to rid himself of depression, self-doubt, and the lessons of his "Bible-thumping father." Still, Knotts' daughter, Karen, remembered: "He was mercurial