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2.3 Wound Healing and Tissue Regeneration: GHK-Cu promotes angiogenesis by enhancing VEGF (vascular endothelial growth factor) expression, accelerating blood vessel formation

Symptoms of Oxidative Stress: It's internal mainly, but manifests as accelerated aging, chronic diseases, and fatigue

On the one hand, the C-to-T substitution at GCLM rs41303970 leads to less GCLM enzyme production 28

Overall, the inherent anti-oxidative ability of GHK promotes wound healing by reducing inflammatory response, and this ability is further enhanced by the introduction of cell surface-reactive cell-targeting peptide

The cytoprotective role of Sp was further evaluated through determination of mitochondrial function and amount of intracellular lipid peroxides quantified by measuring the levels of their decomposed carbonyl product malondialdehyde