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It depends on the specific condition

This powerful detoxification process can subsequently lead to improved skin health, giving it a brighter, more youthful appearance

Townsend Letter 8690 James SJ, Rose S, Melnyk S, Jernigan S, Blossom S, Pavliv O, Gaylor DW (2009) Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism

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This was found not to be sex-dependent, as the rescue was observed in both the female and male mice