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Despite this 9% decrease, smoking prevalence remains well above the European average

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The classic GSM blend (Grenache, Syrah, Mourvdre) is very common in this wine, with Grenache often being the dominant grape

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Management differs because you will treat vaginal atrophy with topical estrogen and lubrication, but vaginal leukoplakia often requires removal of irritants, topical or systemic agents guided by biopsy, and sometimes surgical excision for refractory lesions