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Mendelian randomization analysis also revealed that FGF21 has a beneficial relationship with potential genetic factors associated with aging

However, gut microbiota can produce a variety of polysaccharide hydrolases to degrade dietary fiber and utilize it as an energy source (116)

Tirzepatide's dual mechanism allows for a higher dose ceiling because the GIP component modulates the gastrointestinal effects that would otherwise limit dosing

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METTL3 deposits m 6 A marks on CHAC1 transcripts, leading to their recognition by YTHDF2 and subsequent degradation