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While you cannot be strictly allergic to pure nicotine, an individual can experience extreme allergic hypersensitivity to the thousands of chemical combustion toxins, acrid gases, and formaldehyde compounds embedded inside burning tobacco smoke clouds

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Our analysis relies on modelled estimates of smoking-attributable mortality from GBD 2019, which come with uncertainty intervals (addressed by our upper- and lower-bound sensitivity analysis) and inherently assume that smoking is the primary differentiating factor between the smoker and non-smoker groups

Maintenance, durability and reliability A heated tobacco device needs regular cleaning, a vape mostly needs you to swap a coil and not much else