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[14] Systemic disease [edit] Aphthous-like ulceration may occur in association with several systemic disorders (see table)

Thus, she sank further into herself, as if to make up for the density of being she had lost

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Aging is associated with increasing DNA damage, and the repair machinery, containing DNA methyltransferases and the Polycomb repressive complex, appears to favor CpG-rich regionsincluding the ones we refer to as Polycomb targetsas substrates for de novo methylation [99, 110]

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