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Guan Q, Liao X, He M, Li X, Wang Z, Ma H, Yu S, Liu S

In rats, the extract also had a hypotensive effect, possibly by inhibiting SNS activity (424)

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This metabolite specifically targets and stabilizes PD-L1, which suppresses the activity of tumor-infiltrating T lymphocytes and leads to increased recruitment and activity of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs) and tumor-associated macrophages (TAMs) (46)