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The margin of exposure values were calculated for individual exposure (Figure 1), population-based exposure calculated from prevalence data (Figure 2) and population-based exposure calculated from sewage analysis (Figure 3)

Given that the gum had a relatively low C max and AUC compared with the NP, lozenge and published cigarette PK data, these results suggest that factors other than nicotine PK play an important role in overall likeability of a nicotine product

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So, if you smoke Cuban cigars, youre smoking hybrid cigar tobacco

EX is the culmination of several years of research and testing, combining an understanding of the power of nicotine addiction with messages that resonate with and motivate smokers toward behavior change