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Addiction occurs when chronic exposure to nicotine induces the nervous system to adapt physiologically

According to the most recent available data, Alaskas smoking rate is above the national average at 14.7 percent

The study adheres to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines 16

Altria dominates the list with 46% market share, but the proposed combination of Reynolds American and Lorillard -- expected to close in the first half of 2015 -- would create an entity with almost 39% market share, challenging Altria

Association between smoking and non-alcoholic fatty liver disease: a systematic review and meta-analysis