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16 shows phosphorylation of the c-Met receptor following a 30 minute treatment with vehicle and various concentrations HGF or Dihexa

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Hepatic SIRT1 knockdown or systemic SIRT1 inactivation exacerbates HFD-induced hepatic steatosis, while SIRT1 overexpression attenuates liver damage and improves metabolic profiles [13,14]

Figure 3 The G6PD5.4 and G6PD5.5 proteoforms localize to different subdomains of the ER To determine the exact subcellular localization of the alternative G6PD5 proteoforms, the GFP- and OFP-based reporter fusions were used for co-expression with oppositely labeled organelle markers