Recently, our group has demonstrated that PD mimetics including 6-hydroxydopamine (6-OHDA), N-methyl-4-phenylpridine (MPP + ) and rotenone suppressed mTOR signalling, accelerated cleavage of caspase-3 and PARP in PC12 cells and primary neurons and subsequently triggered neuronal apoptosis
Nowrouzian, F
[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Shabalala S.C., Johnson R., Basson A.K., Ziqubu K., Hlengwa N., Mthembu S.X.H., Mabhida S.E., Mazibuko-Mbeje S.E., Hanser S., Cirilli I., et al
DTT is a reducing agent that is normally added to prevent GSH oxidation in membrane vesicle studies
Capture of the samples was made by hybridizing 2 g of each sample for 40 h, with the custom biotinylated RNA baits