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However, if you have specific sensitivities or concerns, its recommended to perform a patch test or consult with a dermatologist before use

Thorne uses the unhydrolyzed form specifically because it demonstrates enhanced bioactivity compared to hydrolyzed alternatives meaning the natural protein structure is preserved rather than broken down during processing

Individuals with known B12 deficiencies, or those prone to a potential deficiency due to their lifestyle, must supplement vitamin B12

Utzschneider KM, Kratz M, Damman CJ, Hullar M

But the mechanism behind Epithalons sleep effect is indirect and distinct from other peptides that act on sleep directly, a distinction that matters for patient selection