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[87] This trial was the first to report a survival advantage from chemotherapy in malignant pleural mesothelioma, showing a statistically significant improvement in median survival from 10 months in the patients treated with cisplatin alone to 13.3 months in the group of patients treated with cisplatin in the combination with pemetrexed and who also received supplementation with folate and vitamin B 12

Project MIX included chemical analysis of smoke, in vitro mutagenicity and cytotoxicity testing, and in vivo rat inhalation toxicology studies

Merlo, president and CEO of CVS Caremark, said in a statement