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These beneficial effects may additionally be mediated via the 7 nicotinic receptor as this receptor subtype also enhances the antidepressant effects of serotonin uptake blockers ( Finally, nicotine replacement therapy (NRT, with gum, transdermal patch, intranasal spray and inhaled and oral preparations) has high-quality evidence that all of the licensed forms of NRT support people who want to quit smoking

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The primary difference is the amount of nicotine in each pouch

Consumption of tobacco is affected both by the number of people who smokesee Chapter 1) and the amounts of tobacco they consume (see Chapter 2)