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[Abstract]2025 Oct;20(4):2084-2091

Cardiovascular system Studies on acute and medium-term exposure to PET MNPs in mammals point to their potential detrimental effects on the cardiovascular system, mainly through induced oxidative stress, apoptosis, and changes in serum biochemical parameters

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Thaler, C

Comprehensive Preclinical In Vivo Data: Before initiating human studies, a preclinical programme of in vivo studies in animal models is crucial to assess the safety and efficacy of the drug candidate