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J Steroid Biochem Mol Biol 2016;155:104-11

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Previous studies have shown that oncogenic KRAS drives extensive metabolic rewiring in PDAC, including alterations in glycolytic flux 19,20 and autophagy/mitophagy, 24,37 as well as shifts in amino acid, 22 lipid 38 and cholesterol 39 metabolism

Gomez-Florit M, Pardo A, Domingues RMA, Graa AL, Babo PS, Reis RL, et al