Therefore, in the three severity levels, relative weights should increase by severity, from lowest to highest
Statistical significance was assessed by one-way ANOVA followed with Dunnets multiple comparisons test in d, q , by ordinary two-way ANOVA followed by dks multiple comparisons test in e , r , and by ordinary two-way ANOVA followed Tukeys multiple comparisons test in j-o
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In agreement with these reports, Doxorubicin induced senescence in IMR90 in vitro , evident by elevated SA--GAL activity, expression of p16 ink4a , and the early and late SASP factors IL-1 and IL-6 (Orjalo et al., 2009), respectively (Fig
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