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On the pharmacology side, HGF-induced MET activation exerts beneficial neuroprotective effects also in adulthood, specifically in neurodegenerative disease, and in preclinical models of cerebral ischemia, spinal cord injuries, and neurological pathologies, such as Alzheimers disease (AD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS)

The magnitude of heart rate increase in clinical trials was generally small and not clinically significant for most participants

The functional outcomes measured included the Glasgow Outcome Scale (GOS) and modified Rankin Scale (mRS), both standard measures of neurological recovery

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Human Trial Data: What We Actually Have This is where intellectual honesty requires a gear shift