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any thoughts

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Similar to neuronal nuclear inclusions, the axonal ATXN3 aggregates were ubiquitinated and immunopositive for the proteasome and autophagy-associated shuttle protein p62 [23, 30], strengthening the involvement of neuronal protein quality control (PQC) mechanisms in the management of this mutant protein

The stirring continued for another 12 h at room temperature, after which the mixture was transferred into 10 mL of deionized water while being sonicated

It is a clear red injectable solution