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Key Dates Include: Pre-release: December 4, 2024 Open for proposal submissions: January 8, 2025 DSIP Topic Q&A Closure: January 22, 2025, at 10:00 AM MT Close for proposal submissions: February 5, 2025, at 10:00 AM MT Participating DoD Components: Department of the Navy (Navy) Department of the Air Force (Air Force) Defense Health Agency (DHA) Missile Defense Agency (MDA) For further details on active topics and the submission process, you can explore the DoDs SBIR/STTR portal here

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Additionally, ketogenic diets, in theory, can also have a similar impact to calorie restriction, by downregulation of IGF-1 and insulin, promoting PI3K inhibition function, and through increased exposure to oxidative stress for the tumour cells [148,149,150]

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5g) and increased Cxcl1 expression (Fig