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Fertility Oxidative stress affects early embryo development and implantation

Desiere F, Deutsch EW, King NL et al (2006) The PeptideAtlas project

It performs many roles, but primarily it acts as your most powerful antioxidant, combating free radicals and oxidative stress that can slow and eventually break down cellular function

The other mutation (C497S) and the truncation as well as the mentioned mutation of U498S were introduced to obtain stable protein complexes for crystallization