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A loss-of-function shRNA targeted screen in metastatic-derived cells identified Gstt1 , a member of the glutathione S -transferase superfamily, as uniquely required for dissemination and metastasis, but dispensable for primary tumour growth

However, the plasma IL-13 and IL-1 concentrations remained unchanged between groups ( Figures 6G, H )

Toloza EM, Hunt K, Swisher S , McBride W, Lau R, Pang S, Rhoades K, Drake T, Belldegrun A, Glaspy J, Economou JS

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Its a non-invasive and safe procedure, and can be administered as a shot (in the muscle) or through the vein (by IV or push)