Common effects usually mild and often worst during titration include nausea, vomiting, diarrhea, constipation, abdominal pain, upset stomach, headache, and fatigue
In their review, Doets et al
NNMT inhibition combined with exercise enhances skeletal muscle endurance and grip strength in aged mice
The following data were collected: publication year, country and continent, study setting (e.g., hospital, private practice, academic clinic), sample size, age range, mean age, study design, population characteristics, intervention details, outcomes, and effect measures (e.g., serum B12 levels)
Consider complementary NAD+ precursors (NMN/NR) per emerging stack protocols [8]